8 | NUR 515 | Saint Thomas University

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Neurotransmitter Table

Neuro

transmitter

Receptor

Subtype

Location/Function/Effects/symptoms of excess or deficit if applicable

Distribution

(ie: CNS/PNS, GI, vascular)

Drug classes that target this neurotransmitter or receptor

Specific medications that target this neurotransmitter or receptor

Glutamate

AMPA

NMDA

GABA

GABA a

GABA b

Serotonin

5HT

5HT 1a

5HT 1B

5HT 1d

5HT 1E

5HT 1F

5HT 2A

5HT2B

5HT 2C

5HT 3

Ligand gated ion channels. highest levels in the brain stem-

Targets: decreases nausea/emesis

Will inhibit the release of NE and Ach-

Targets: cognition, anxiety, addiction.

CNS

(chemoreceptor trigger zone)

PNS:

GI tract (vagal nerve)

Antiemetics

Antidepressants

Antiemetics:

ondansetron, granisetron, 

dolasetron, palonosetron

Antidepressants:

Mirtazapine

vortioxetine

5HT 4

5HT 5 AB

5HT6

5HT 7

NE

norepinephrine

α 1

α 2

DA

Dopamine

D1

D2

D3

D4

Ach

Acetylcholine

Muscarinic

Nicotinic

Histamine

Melatonin

1. For each neurotransmitter and receptor type, complete the following columns:

a. Location/function/effects/symptoms of excess or deficit

b. Distribution

c. Drug classes that target this neurotransmitter or receptor

d. All neurotransmitters and receptor types: Specific medications that target this neurotransmitter or receptor

2. This criterion is linked to a Learning Outcome Organization

3. Font is consistent throughout table, and grammar, spelling, and/or punctuation are accurate.

A total of 4 references needed with intext citation. 2 references provided below. Please use 7th edition APA scholarly references that are witin 5 years.

Stahl, S.M. (2020). Stahl’s essential psychopharmacology: Prescribers guide (7th ed.). Cambridge University Press.

Stahl, S. M. (2021). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (5th ed.). Cambridge University Press.

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