11.The structure below represents a fatty acyl CoA molecule, formed in the first step of ?-oxidation of a fatty acid. Which of the following statements concerning this compound is true?
A) The wavy line indicates a partially formed thioester bond.
B) The wavy line indicates an ionic bond between the fatty acid and coenzyme A.
C) The wavy line indicates a high-energy thioester bond.
D) The wavy line indicates a highly polar bond between the fatty acid and coenzyme A.
E) The wavy line indicates a partially formed disulfide bond.
12.What type of compound is produced from acetyl CoA when there is insufficient oxaloacetate to allow all the acetyl CoA to enter the citric acid cycle?
A) amino acids
B) glycogen
C) disaccharides
D) ketone bodies
E) nucleotides
13.What metabolic pathway produces ?-hydroxybutyrate, acetone, and acetoacetate?
A) ?-oxidation
B) ketogenesis
C) acidosis
D) lipogenesis
E) glycolysis
14.Why must dietary triglycerides be processed before digestion begins?
A) Dietary triglycerides are large, hydrophobic molecules that must be emulsified by bile salts in order for lipases to be effective.
B) Dietary triglycerides are more stable and undergo hydrolysis more readily when they are bound to the surface of micelles.
C) Dietary triglycerides contain glycerol as part of their structure; glycerol is toxic to the cell and must first be removed.
D) Dietary triglycerides are acidic molecules that must be made basic for entry into the small intestine.
E) Dietary triglycerides are basic molecules that must be made acidic for entry into the small intestine.
15.Which statement describing ?-oxidation of fatty acids and fatty acid biosynthesis is FALSE?
A) ?-Oxidation occurs in the mitochondria.
B) The acyl group carrier in ?-oxidation is coenzyme A.
C) The electron carriers in ?-oxidation and biosynthesis are NADH and FADH2.
D) The acyl group carrier in biosynthesis is acyl carrier protein (ACP).
E) Biosynthesis occurs in the cytoplasm.
16.Which type of lipoprotein complex transports triglycerides made by the liver to adipose tissue?
A) chylomicrons
B) coenzyme A
C) adipocytes
D) very low density lipoproteins (VLDL)
E) triglyceride transportase complex
17.What is the source of energy for the activation of a fatty acid in ?-oxidation?
A) phosphorylation of AMP
B) hydrolysis of the thioester bond in acetyl CoA
C) hydrolysis of ATP to AMP
D) conversion of NADH to NAD+
E) oxidation of glycerol
18.What is the major storage form of fatty acids in the body?
A) glycogen
B) triglycerides
C) cellulose
D) protein
E) lipoproteins
19.The third reaction in ?-oxidation of fatty acids is shown below, and involves hydration of the double bond. What is the product of this reaction?
A)
B)
C)
D)
E)
20.What process generally supplies the energy requirements of resting muscle?
A) glycolysis
B) protein degradation
C) urea cycle
D) ?-oxidation of fatty acids
E) glycogenolysis
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