In “The Ethics of Clinical Trials in the Third World” Marcia Angell likens the AZT clinical trials to the infamous Tuskegee Study. Her core argument is that it is wrong to use a placebo-controlled study when a state of clinical equipoise does not obtain. First, what is clinical equipoise? Why does Angell think the shorter course should have been tested against the standard (or full) course of AZT?
Don Marquis rejects clinical equipoise as the standard for judging the merits of a study. He argues that informed consent is the key to assessing the morality of a study. Do you think pregnant HIV+, scientifically illiterate African women in the study conducted by Bagenda and Mudido were capable of giving informed consent? (Be careful here—to say women in such circumstances are incapable of giving informed consent smacks of paternalism.)
Brody defends the study. On his view, there is a key difference between the study conducted by Bagenda and Mudido and the Tuskegee Study. In the latter, medication that was readily available was intentionally withheld. In Uganda, AZT is not readily available. One point is clear. The shorter course of AZT was effective. Do you think the study by Bagenda and Mudido is morally permissible? Defend your answer.
Core question: Is Angell’s comparison of the AZT Studies comparable with the Tuskegee Study? Defend your answer.
(Minimum World Count: 500 Words)
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.
Read moreEach paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.
Read moreThanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.
Read moreYour email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.
Read moreBy sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.
Read more